Showcase Materials: Advancing Bioanalytical Research

At Sound Analytics, we are dedicated to pushing the boundaries of high-throughput bioanalysis through innovative software and hardware solutions. Our collaborations with leading pharmaceutical research groups have resulted in groundbreaking advancements in LC/MS workflows, automation, and data-driven methodologies.

This page highlights our contributions to major industry conferences, including ASMS and CPSA, where we have presented on cutting-edge techniques in drug discovery, ADME, and bioanalytical mass spectrometry. Explore our showcase materials to see how our technology is shaping the future of pharmaceutical research.

GSK-US-DMPK Bioanalytical Workflow: In Vitro Assays

Exploring our cutting-edge bioanalytical workflow for both standard and high-throughput in vitro assays, powered by Sciex and Sound Analytics solutions.

(GSK, Sciex, Sound Analytics)

ASMS 2019 Session: Drug Discovery/DMPK/ADME I – WP 246

Dual-Stream LC coupled with ‘plug and play’ automation for routine bioanalysis in drug discovery

(Genentech, Sciex, Sound Analytics)

ASMS 2019 Session: Drug Discovery/DMPK/ADME I – WP 247

Design and Optimization of an Integrated Trap-and-Elute Microflow LC-MS/MS Platform

(Pfizer Inc, Sound Analytics, J2-Bioanalytical)

ASMS 2019 Session: LC/MS: Chromatography and Software II – ThP 334

Optimization and Selection of Assigned Charge State Conditions for LC/MS/MS High Throughput Bioanalysis

(Pfizer Inc, Sound Analytics)

ASMS 2019 Session: LC/MS: Chromatography and Software II – ThP 335

Multiplexing Independent Streams to Increase LC/MS/MS Throughput

(Pfizer Inc, Sound Analytics)

LeadScape_Prolab microflow CPSAOct2018_bn

LeadScape/LS-I – micro-flow workstation plans 16OCT2018

ASMS 2018 Session: Drug Discovery/DMPK/ADME I – MP 191

Design And Integration Of A High-Performance Micro-Flow LC-MS/MS System

(Pfizer Inc, ProLab, Sound Analytics)

ASMS 2017 Session: Drug Metabolism/Quantitative Analysis – TP 153

Development of High-Performance Micro-flow LC-MS/MS Methodology and Application to a High-Throughput Screening Workflow

(Pfizer Inc, Sound Analytics)

ASMS 2017 Session: Drug Discovery/DMPK/ADME – MP 146

LeadScape: An automated platform for LC/MS/MS methods development, storage and distribution

(Pfizer Inc, Sound Analytics)

ASMS 2016 Session: Drug Metabolism/Qualitative and High Throughput Analysis – 142

Dual-stream UHPLC separations on a compact sample delivery system featuring simplified software automation for increased throughput in drug discovery bioanalysis

(Sound Analytics, Pfizer Inc)

ASMS 2016 Session: Drug Discovery/DMPK/ADME – 156

Application of High-Throughput Micro-Flow LC/MS/MS to a Metabolic Stability Screening Workflow

(Pfizer Inc, Sound Analytics)

ASMS 2016 Session: Drug Metabolism/Quantitative Analysis – 107

Evolution, Development, and Application of a Dynamic, High-Throughput, Enterprise-Level Autosampler for High-Performance LC/MS/MS Bioanalysis

(Pfizer Inc, Sound Analytics)

ASMS 2015 Session: Drug Metabolism/High Throughput Analysis – 236

Open-Access LC/MS/MS Platform for Rapid Bioanalysis in Drug Discovery

(Sound Analytics, Pfizer Inc)

ASMS 2015 Session: Drug Metabolism/High Throughput Analysis – 244

High-Throughput Quantitative Analysis of Low Molecular Weight Substrates using Liquid Chromatography Coupled with High Resolution Mass Spectrometry (HRMS)

(Pfizer Inc, Sound Analytics)

ASMS 2015 Session: Drug Metabolism/High Throughput Analysis – 246

High-Throughput, Dual-Stream Micro-flow LC/MS/MS Bioanalysis

(Pfizer Inc, Sound Analytics, TwoCenter Technologies)

ASMS 2015 Session: Metabolomics/Quantitative Analysis – 393

Automated LC/MS/MS methods development for targeted bioanalysis of metabolic intermediates

(Pfizer Inc, Sound Analytics)

ASMS 2014 Session: Quantitative Analysis in Drug Discovery and Development

High-Throughput, Dual-Stream UHPLC/MS/MS Bioanalysis and Data-Deconvolution for Rapid Drug Discovery Applications

(Pfizer, Sound Analytics, Two Center Technologies)

ASMS 2014 Session: Quantitative Analysis in Drug Discovery and Development – 627

The ADME-Hub: Formalizing and Automating Information Flow in the Preparation and Measurement of Lead Optimization Assays

(Sound Analytics, TwoCenter Technologies, Pfizer Inc)

ASMS 2013 Session: High Throughput Analysis/Robotics – 185

Chromatographic Optimization, Storage, and Re-use in a Combined High Throughput Compound Optimization Workflow Using a Dual Arm Autosampler

(Sound Analytics, TwoCenter Technologies, Pfizer Inc)

ASMS 2013 Session: Drug Metabolism: High Throughput – 039

Optimizing High-Throughput LC/MS/MS “Trap-and-Elute” Bioanalysis in Drug Discovery

(Pfizer, Sound Analytics)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 353

The ADME Hub: Desktop Software for Linking Metabolic Profiling Assays and LC/MS/MS Bioanalysis in Drug Discovery

(Sound Analytics, TwoCenter Technologies, Pfizer)

ASMS 2012 Session: High Throughput Analysis/Robotics – 364

High-Speed Integrated FIA Method Development and Metabolic Stability Assays on a Dual-Arm Autosampler

(Sound Analytics, TwoCenter Technologies, Pfizer)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 352

Automation and Standardization of the Compound Optimization Process for Data Consolidated in a Shared SQL Server Database

(Merck Research Laboratories, Sound Analytics)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 349

Fully Integrated High Throughput System for ADME Screens Using Cassette Analysis

(Pfizer, Sound Analytics, Apricot Designs)

ASMS 2011 Session: PK Assays: Novel Approaches to Increase LC-MS Throughput

Next generation sample delivery platform for HT-LC/MS/MS

(Pfizer, Apricot Designs, Sound Analytics)

ASMS 2011 Session: Drug Metabolism: High Throughput/Robotics – 213

Collaborative methods development in drug discovery

(Pfizer, Sound Analytics, AB Sciex)

ASMS 2010 Session: Peptides: Quantitation Methods – 172

A novel software algorithm for high-throughput optimization of quantitative MS/MS parameters for peptide quantitation and alteration/modification screening.

(AB Sciex, Sound Analytics)

ASMS 2010 Session: Drug Metabolism: High Throughput – 508

Comparison of Automated MS/MS Tuning Algorithms for HT- Methods Development in Drug Discovery

(Pfizer, AB Sciex, Sound Analytics)

ASMS 2010 Session: High Throughput Analysis/Robotics – 563

A novel algorithm for automated high-throughput quantitative MS/MS optimization incorporating saturation control

(AB Sciex, Sound Analytics, Pfizer)

ASMS 2009 Session: High Throughput Analysis/Robotics – 679

Evaluation of New Version DiscoveryQuant™ Software for Automated MRM Generation and Quantitation for in vitro ADME Screening

(AstraZeneca, Sound Analytics, AB Sciex)

ASMS 2008 Session: Quantitation of Small Molecules/Pharmaceutical Focus – 203

Practical Automated Algorithm Design for High Throughput Method Optimization in ADME/PK Environments

(Applied Biosystems, Sound Analytics, Pfizer)

ASMS 2008 Session: Drug Metabolism Pharmacokinetics – 320

Hardware and Software Design Strategies for the Rapid Determination of Optimal Quantitative MS/MS Conditions.

(Applied Biosystems, Pfizer, Sound Analytics)

ASMS 2008 Session: High Throughput Analysis/Robotics – 154

Automatic MS/MS methods development utilizing an IDA-logic approach to enhance the specificity and range of optimized parameters

(Pfizer, Sound Analytics, Applied Biosystems, MDS Analytical Technologies, MDS Sciex)

ASMS 2008 Session: Drug Metabolism: High Throughput – 246

Integration of hardware and software systems for high-throughput sample processing in ADME-screening bioanalysis

(Pfizer, MDS Sciex, Sound Analytics)

ASMS 2007 Session: Computer Applications – 171

Automatic MS/MS methods development using an information dependent scanning protocol to enhance sensitivity for high-throughput ADME screening and drug discovery.

(Pfizer, Sound Analytics, Applied Biosystems/Sciex)