Publications

 

ASMS 2016 Session: Drug Metabolism: Qualitative and High Throughput Analysis – 142
Dual-stream UHPLC separations on a compact sample delivery system featuring simplified software automation for increased throughput in drug discovery bioanalysis
(Sound Analytics, Pfizer Inc)

ASMS 2016 Session: Drug Discovery/DMPK/ADME – 156
Application of High-Throughput Micro-Flow LC/MS/MS to a Metabolic Stability Screening Workflow
(Pfizer Inc, Sound Analytics)

ASMS 2016 Session: Drug Metabolism: Quantitative Analysis – 107
Evolution, Development, and Application of a Dynamic, High-Throughput, Enterprise-Level Autosampler for High-Performance LC/MS/MS Bioanalysis
(Pfizer Inc, Sound Analytics)

ASMS 2015 Session: Drug Metabolism: High Throughput Analysis – 236
Open-Access LC/MS/MS Platform for Rapid Bioanalysis in Drug Discovery
(Sound Analytics, Pfizer Inc)

ASMS 2015 Session: Drug Metabolism: High Throughput Analysis – 244
High-Throughput Quantitative Analysis of Low Molecular Weight Substrates using Liquid Chromatography Coupled with High Resolution Mass Spectrometry (HRMS)
(Pfizer Inc, Sound Analytics)

ASMS 2015 Session: Drug Metabolism: High Throughput Analysis – 246
High-Throughput, Dual-Stream Micro-flow LC/MS/MS Bioanalysis
(Pfizer Inc, Sound Analytics, TwoCenter Technologies)

ASMS 2015 Session: Metabolomics: Quantitative Analysis – 393
Automated LC/MS/MS methods development for targeted bioanalysis of metabolic intermediates
(Pfizer Inc, Sound Analytics)

ASMS 2014 Session: Quantitative Analysis in Drug Discovery and Development
High-Throughput, Dual-Stream UHPLC/MS/MS Bioanalysis and Data-Deconvolution for Rapid Drug Discovery Applications
(Pfizer, Sound Analytics, Two Center Technologies)

ASMS 2014 Session: Quantitative Analysis in Drug Discovery and Development – 627
The ADME-Hub: Formalizing and Automating Information Flow in the Preparation and Measurement of Lead Optimization Assays
(Sound Analytics, TwoCenter Technologies, Pfizer Inc)

ASMS 2013 Session: High Throughput Analysis/Robotics – 185
Chromatographic Optimization, Storage, and Re-use in a Combined Highthroughput Compound Optimization Workflow Using a Dual Arm Autosampler
(Sound Analytics, TwoCenter Technologies, Pfizer Inc)

ASMS 2013 Session: Drug Metabolism: High Throughput Analysis – 039
Optimizing High-Throughput LC/MS/MS “Trap-and-Elute” Bioanalysis in Drug Discovery
(Pfizer, Sound Analytics)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 353
The ADME Hub: Desktop Software for Linking Metabolic Profiling Assays and LC/MS/MS Bioanalysis in Drug Discovery
(Sound Analytics, TwoCenter Technologies, Pfizer)

ASMS 2012 Session: High Throughput Analysis/Robotics – 364
High-Speed Integrated FIA Method Development and Metabolic Stability Assays on a Dual-Arm Autosampler
(Sound Analytics, TwoCenter Technologies, Pfizer)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 352
Automation and Standardization of the Compound Optimization Process for Data Consolidated in a Shared SQL Server Database
(Merck Research Laboratories, Sound Analytics)

ASMS 2012 Session: Drug Metabolism: High Throughput Analysis – 349
Fully Integrated High Throughput System for ADME Screens Using Cassette Analysis
(Pfizer, Sound Analytics, Apricot Designs)

ASMS 2011 Session: PK Assays: Novel Approaches to Increase LC-MS Throughput
Next generation sample delivery platform for HT-LC/MS/MS
(Pfizer, Apricot Designs, Sound Analytics)

ASMS 2011 Session: Drug Metabolism: High Throughput/Robotics – 213
Collaborative methods development in drug discovery
(Pfizer, Sound Analytics, AB Sciex)

ASMS 2010 Session: Peptides: Quantitation Methods – 172
A novel software algorithm for high-throughput optimization of quantitative MS/MS parameters for peptide quantitation and alteration/modification screening.
(AB Sciex, Sound Analytics)

ASMS 2010 Session: Drug Metabolism: High Throughput – 508
Comparison of Automated MS/MS Tuning Algorithms for HT- Methods Development in Drug Discovery
(Pfizer, AB Sciex, Sound Analytics)

ASMS 2010 Session: High Throughput Analysis/Robotics – 563
A novel algorithm for automated high-throughput quantitative MS/MS optimization incorporating saturation control
(AB Sciex, Sound Analytics, Pfizer)

ASMS 2009 Session: High Throughput Analysis/Robotics – 679
Evaluation of New Version DiscoveryQuantTM Software for Automated MRM Generation and Quantitation for in vitro ADME Screening
(AstraZeneca, Sound Analytics, AB Sciex)

ASMS 2008 Session: Quantitation of Small Molecules/Pharmaceutical Focus – 203
Practical Automated Algorithm Design for High Throughput Method Optimization in ADME/PK Environments
(Applied Biosystems, Sound Analytics, Pfizer)

ASMS 2008 Session: Drug Metabolism Pharmacokinetics – 320
Hardware and Software Design Strategies for the Rapid Determination of Optimal Quantitative MS/MS Conditions.
(Applied Biosystems, Pfizer, Sound Analytics)

ASMS 2008 Session: High Throughput Analysis/Robotics – 154
Automatic MS/MS methods development utilizing an IDA-logic approach to enhance the specificity and range of optimized parameters
(Pfizer, Sound Analytics, Applied Biosystems, MDS Analytical Technologies, MDS Sciex)

ASMS 2008 Session: Drug Metabolism: High Throughput – 246
Integration of hardware and software systems for high-throughput sample processing in ADME-screening bioanalysis
(Pfizer, MDS Sciex, Sound Analytics)

ASMS 2007 Session: Computer Applications – 171
Automatic MS/MS methods development using an information dependent scanning protocol to enhance sensitivity for high-throughput ADME screening and drug discovery.
(Pfizer, Sound Analytics, Applied Biosystems/Sciex)